The seralini study has since been rejected worldwide by various international food safety organizations including african unions african biosafety network of expertise abne and the european food safety authority efsa and all appropriate scientific bodies in france. Ten things you need to know about the seralini study gmo. The european food safety authority efsa evaluated the study as defective based on conceptual and methodological shortcomings by retroactive application of the recommendations of its recent guidance on 90day. The monod study did not show significant differences in weight gain between gm maize fed animals and controls, except for a marginal statistically significant difference in the rate of growth of female rats at the highest dose applied 33%, during part of the study period, while the final total weight was not affected. A recent paper published in the journal food and chemical toxicology presents the results of a longterm toxicity study related to a widelyused commercial herbicide roundup and a rounduptolerant genetically modified variety of maize, concluding that both the herbicide and the maize varieties are toxic. Debate on gmos health risks after statistical findings in. In our precise file, the genetic modification has been. Oct 05, 2010 also in this case of multiple comparisons, the study of the false positives is not specific to the student t test, and is not treated in these monsantos studies. All earlier studies investigated glyphosate, the herbicidal ingredient of. Elsevier has announced that they are retracting the infamous seralini study which claimed to show that gmo corn causes cancer in laboratory rats. Gileseric seralini, a professor of molecular biology at caen university, led a toxicological study on gm maize and roundup herbicide involving 200 rats over a period of two years see. French scientists say gm maize caused tumors in rats. The rest does repeat some of seralini s arguments in favor of his studies for example, that sd rats are used in industryfunded studies too, which is in argument that entirely ducks the criticism that the problem with the choice of rat species is the length of the study and the number used, not the choice of rat species alone the regulatory.
The study was then republished by environmental sciences europe, but only after the studys reputation was wrongly damaged due to the work of monsanto behind the scenes. The experiment was designed for a 90day study, not a 2year study. Some contaminations or pollutions by pesticides 1 and other chemical residues 24 affect human and animal health, together with biodiversity. The gm maize alone was tested on three groups at 11%, 22% and 33% of the total diet. The new study shows that a very low concentration of glyphosate in the parts per trillion range and thus environmentally relevant for everyone can trigger breast cancer when combined with another risk factor. Thus it is important to study potential mid and longterm toxicological effects during regulatory tests prior to commercialization of chemicals, and not to test only shortterm or subchronic effects. Therefore, the tumor incidence and mortality results were reported, according to oecd guidelines for chronic toxicity studies, as secondary observations requiring followup using a study design intended to systematically assess carcinogenesis. A scientific analysis of the rat study conducted by gilleseric seralini.
The corrupt gmo pesticide industry always want to talk about the tumors. The varieties of maize used in this study were the rtolerant nk603 monsanto corp. The french team was led by molecular biologist professor gilleseric seralini. Seralini s 2012 study 1 tested the longterm effects of monsantos gm nk603 maize, which is engineered to survive being sprayed with roundup herbicide, and roundup. It was a chronic toxicity study and a welldesigned and wellconducted one. Report on mon 863 gm maize produced by monsanto company june 2005 controversial effects on health reported after subchronic toxicity test. However, given this study presents serious deficiencies in the protocol, the procedures and the interpretation of the. This was the first study to investigate effects of a roundup formulation. A detailed analysis of the data in the subchronic toxicity studies 25 has. The environmental sciences europe journal has decided to republish the seralini study with additional commentary and findings. Overall, our study is the first indepth lifelong toxicology study on the full commercial roundup formulation and nk603 gm maize, with observations on 34 organs and measurement of 56 parameters analyzed at 11 time points for most organs, and utilizing 3 doses. There is rapid growth in awareness across the globe of gmo. Previously in these pages i discussed how the trial of monsanto currently taking place in the california northern district courttechnically known as multidistrict litigation, with the formal title of in re.
A detailed analysis of the data in the subchronic toxicity studies 25 has revealed statistically significant. Retracting seralini study violates science and ethics. The seralini study numerous studies of laboratory animals fed gm foods have found no evidence of risks to human health efsa gmo panel working group on animal feeding trials 2008. A 2year rat feeding study with genetically modified nk603 maize sparked an international scientific and public debate as well as policy responses by the european commission. Seralinis study concluded that rats fed corn genetically modified for herbicide resistance with or without monsantos roundup herbicide developed tumours, contradicting the conclusions of hundreds of studies that have consistently found no safety issues.
The story behind seralinis disappearing gmosaretoxic. It underlies the concept of transgenics, in which an organism is modified to incorporate new genes that lead to new characteristics, such as the production of proteins for human health, or the expression of a gene for herbicide resistance in plants, to name just two applications. These two types of maize were grown under similar normal conditions, in the same location, spaced at a suf. Here we discuss the many errors and inaccuracies in the published article resulting. In this study researchers led by gilleseric seralini from criigen have found that rats fed on a diet containing nk603 roundup tolerant gm maize or given water containing roundup, at levels permitted in drinking water and gm crops in the us, developed cancers faster and died earlier than rats fed on a. How ever, several studies consisting of 90 day rat feeding trials have been. Jun 24, 2014 the letter criticized the seralini study on several fronts, and concluded. Seralini study on gmo toxicity disappears after one day.
This article or excerpt is included in the glps daily curated selection of ideologically diverse news, opinion and. European food safety authority denounces seralinis antigm food study n fly maggots that clean wounds and kill drug resistant germs will soon be the. The study used 200 rats divided into ten groups, each of ten males and ten females. Longterm toxicity of a roundup herbicide and a rounduptolerant genetically modified maize, by gilleseric seralini, et.
Report on mon 863 gm maize produced by monsanto company. Scientists react to republished seralini gmo maize rat study. The scientific analysis in this document shows the research design that seralini et al. Apr 18, 2015 new analysis of a rat feeding study with a gmo seralini new analysis of a rat feeding study with a genetically modified maize reveals.
The study was designed as a toxicological study, not as a carcinogenesis study. According to a seralini study there is, solid evidence showing that gmos are processed by mammals far differently than natural foods benson, 20. Monsantos motion in limine 10 to exclude discussion of the seralini study is granted for both phases under rule 403. Gilleseric seralini newest attack on gmos, this one purporting to show that a type of genetically modified corn once used in livestock feed can be toxic, has disappeared from the web. According to a seralini study there is solid evidence. How subchronic and chronic health effects can be neglected. Seralini s study is the only longterm study on the commercialized gm maize nk603 and the pesticide roundup it is designed to be grown with. Seralini study republished in the environmental sciences. In light of these concerns regarding the study, it would be an enormous stretch to say the study proves that these corn varieties cause organ damage in mammals. For instance, numerous food safety studies have been carried out on various genetically modified crops whereby the crops were fed to these rats.
Public perception on labeling of genetically modified gm. But the study is currently available to read for free, and you can see a youtube clip of him discussing this paper, his methods, and his criticisms of monsanto. The letter criticized the seralini study on several fronts, and concluded. Rat feeding studies with genetically modified maize a. The retraction comes one year after the paper was published, and seems to be a response to the avalanche of criticism the study has faced. Jun 24, 2014 there is an ongoing international debate as to the necessary length of mammaliantoxicity studies, including metabolic analyses, in relation to the consumption ofgenetically modified gm plants. Donate 5 or more towards the 50 000 project for independent research gilleseric seralini, professor of molecular biology at caen university and a member of the committee for independent research and information on genetic engineering criigen is internationally well known and respected for independent research on the toxicology of. Thus it was essential to suggest a study of the false positives. In this study researchers led by gilleseric seralini from criigen have found that rats fed on a diet containing nk603 roundup tolerant gm maize or given water containing roundup, at levels permitted in drinking water and gm crops in the us, developed cancers faster and died earlier than rats fed on a standard diet. In other words, the statements that seralini made about the health effects of gmos and roundup were baseless.
The health effects of a rounduptolerant genetically modified maize from 11% in the diet, cultivated with or without roundup, and roundup alone from 0. Currently, no regulatory authority requires mandatory chronic animal feedingstudies to be performed for edible genetically modified organisms gmos, or evenshortterm studies with blood analyses for. Scienceafrica journalist european food safety authority. The seralini affair was the controversy surrounding the publication, retraction, and republication of a journal article by french molecular biologist gilleseric seralini. In the study, scientists exposed noncancerous human breast cells to glyphosate in vitro over a course of 21 days. Biochemical and histopathological studies on female and. New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity. In an announcement made today in france, the seralini study on the long term effects of gmos and glyphosate has been republished in the springer open source journal environmental sciences europe eseu, 2014, 26. Here is a summary of the seralini related documents released on tuesday. New analysis of a rat feeding study with a gmo seralini new analysis of a rat feeding study with a genetically modified maize reveals.
The body weights, food consumption, hematology, serum biochemistry, organ weight, and histopathological examination were compared between rats fed on gm soybean and those. Even if otherwise admissible, evidence of monsantos response to the seralini study would be excluded with respect to hardeman as postuse conduct under monsantos motion in. First published by food and chemical toxicology in september 2012, the article presented a twoyear feeding study in rats, and reported an increase in tumors among rats fed genetically modified corn and the herbicide roundup. That article was subsequently retracted by the journal publisher, followed by an explanatory note from. Genetic modification gm is the alteration of the genome of a plant or animal by the addition of new genetic material. The aim of this study was to evaluate the effects of a diet containing gm soybean meal rur on male and female wistar rats. Roundup ready became the most cultivated genetically modified gm crop in the world. A scientific analysis of the rat study conducted by gilles. Also in this case of multiple comparisons, the study of the false positives is not specific to the student t test, and is not treated in these monsantos studies. Our analysis of currently published evidence confirms nk603 and roundup are kidney and liver toxicants at levels below current regulatory thresholds.
Jun 24, 2014 in an apparent attempt to deflect criticism, seralini et al. Personnel discusses plan seeking retraction of seralini glyphosate study. We report here the major toxicological findings on multiple organ systems. This retraction is to the antigmo world what the retraction of the infamous wakefield. Long term toxicity of a roundup herbicide and a roundup. Monsanto secret documents show massive attack on seralini. There is an ongoing international debate as to the necessary length of mammaliantoxicity studies, including metabolic analyses, in relation to the consumption ofgenetically modified gm plants. A paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup seralini et al. It is a simple tactic of focusing on the non issue so that discussion of the very disturbing toxicology findings will be avoided. Long term toxicity of a roundup herbicide and a rounduptolerant genetically modi.
Most criticisms of seralini s study wrongly assume it was a badly designed cancer study. The seralini study was a toxicology study that had nothing to do with cancer. Plaintiffs exhibit monsanto and croplife emails re seralini study retraction. The seralini gmo study retraction and response to critics. The study was originally published in the elsevier journal food and chemical toxicology fct in september 2012, and caused global outcry and alarm in a number of countries who cited the study findings as reason for banning the import of genetically modified organisms. The monod study did not show significant differences in weight gain between gm maize fed animals and controls, except for a marginal statistically significant difference in the rate of growth of female rats at the highest dose applied 33%, during part of the study. In the study, scientists exposed noncancerous human.